Ensiklopedia

ETFDH
Pengidentifikasi
	ETFDH , electron-transferring-flavoprotein dehydrogenase, ETFQO, MADD, electron transfer flavoprotein dehydrogenase
ID eksternal	231675 106100 3275 ETFDH
Lokasi gen (Tikus)
Kr.	Kromosom 3 (tikus)
Akhir	79,536,807 bp
Pola ekspresi RNA
	; ;
	Referensi data ekspresi selengkapnya
Fungsi molekuler	• 4 iron, 4 sulfur cluster binding ; • ubiquinone binding ; • quinone binding ; • flavin adenine dinucleotide binding ; • iron-sulfur cluster binding ; • metal ion binding ; • electron transfer activity ; • oxidoreductase activity ; • electron-transferring-flavoprotein dehydrogenase activity ; • oxidoreductase activity, acting on metal ions, flavin as acceptor ;
Komponen seluler	• membran ; • integral component of mitochondrial inner membrane ; • mitochondrial matrix ; • mitokondria ; • mitochondrial inner membrane ; • mitochondrial membranes ; • mitochondrial electron transfer flavoprotein complex ;
Proses biologis	• fatty acid beta-oxidation using acyl-CoA dehydrogenase ; • GO:0001306 response to oxidative stress ; • Rantai transpor elektron ; • respiratory electron transport chain ;
	Sumber: Amigo / QuickGO
	2110
	66841
	ENSG00000171503
	ENSMUSG00000027809
	Q16134
	Q921G7
	NM_004453 ; NM_001281737 ; NM_001281738
	NM_025794
	NP_001268666 ; NP_001268667 ; NP_004444
	NP_080070
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Oksidoreduktase ETF-Q ( bahasa Inggris : electron-transfer flavoprotein:ubiquinone oxidoreductase, electron-transferring-flavoprotein dehydrogenase, ETF-Q oxidoreductase, ETFQO, EC 1.5.5.1 ) adalah enzim katalis berjenis flavoprotein 4Fe-4S, ^{[

4

]} dengan berkas genetik ETFDH yang berperan dalam proses reduksi senyawa Q -1 dengan elektron dari senyawa , dan oksidasi asam lemak dan beberapa asam amino kemudian mentransfer elektronnya ke dalam rantai pernapasan mitokondria pada kompleks II.

ETF-QO diketemukan oleh dan pada tahun 1975, kemudian, diteliti lebih lanjut oleh dan pada tahun 1985 sehingga karakter senyawa ini dapat diketahui. ^{[

5

]} ETFQ merupakan komponen yang penting pada lintasa oksidasi asam lemak . Defisiensi dan ETF-QO akan mengakibatkan yang fatal yang disebut tipe II.

Rujukan

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027809 - , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ (Inggris) "Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool" . Department of Biochemistry, Medical College of Wisconsin, Department of Pediatrics, University of Colorado Health Sciences Center, California Institute of Technology; Jian Zhang, Frank E. Frerman, Jung-Ja P. Kim dan Douglas C. Rees . Diakses tanggal 2010-11-11 .
^ (Inggris) "Reactions of electron-transfer flavoprotein and electron-transfer flavoprotein: ubiquinone oxidoreductase" . Department of Biochemistry and Biophysics, University of California, Molecular Biology Division, Veterans Administration Medical Center, Department of Chemical Pathology, University of Cape Town Medical School; Rona R. RAMSAY, Daniel J. STEENKAMP dan Mazhar HUSAIN . Diakses tanggal 2010-11-11 .

Artikel bertopik biokimia ini adalah sebuah rintisan . Anda dapat membantu Wikipedia dengan .

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000027809 - , May 2017

[2] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[4] (Inggris) "Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool" . Department of Biochemistry, Medical College of Wisconsin, Department of Pediatrics, University of Colorado Health Sciences Center, California Institute of Technology; Jian Zhang, Frank E. Frerman, Jung-Ja P. Kim dan Douglas C. Rees . Diakses tanggal 2010-11-11 .

[5] (Inggris) "Reactions of electron-transfer flavoprotein and electron-transfer flavoprotein: ubiquinone oxidoreductase" . Department of Biochemistry and Biophysics, University of California, Molecular Biology Division, Veterans Administration Medical Center, Department of Chemical Pathology, University of Cape Town Medical School; Rona R. RAMSAY, Daniel J. STEENKAMP dan Mazhar HUSAIN . Diakses tanggal 2010-11-11 .

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